Analysis of Multiple Genomic Sequence Alignments: A Web Resource, Online Tools, and Lessons Learned From Analysis of Mammalian SCL Loci

Table 1.

Functional Annotation of the Mouse SCL Locus


Region

Open chromatin (approx. location)

Minimally defined active element

Transcription factor binding site
–8/–9 kb 20265–20665 18884–22017 Unknown
20765–21165
–4 kb 24965–25445 25095–25488 Ets family 25213
Ets family 25262
Ets family 25361
Ets family 25369
Promoter 1a 28965–29265 29044–29257 C/EBP 29119
Ap1 29130
Gata1 29162
Sp1 29168
Gata1 29194
Promoter 1b 29425–29585 29440–29558 Sp1/3 29472
Ets family 29494
Ets family 29498
Ets family 29502
C/EBP 29520
+1 kb 29865–30165 29558–30376 Unknown
+3 kb 31865–32065 30377–36071 Unknown
+7 kb 35625–36065 34510–37251 Unknown
+18 kb 47265–47595 47299–47728 Unknown
+19 kb 48045–48345 47728–48369 AATAA 48210
Ets family 48217
Ets family 48237
Gata2 48262
+23 kb
Unknown
50934–52609
Unknown
  • The names of the regulatory regions, approximate regions of open chromatin, the minimally defined active element, and known transcription factor binding sites are indicated. On the Web server, entries in the first column serve as hypertext links to detailed information on the individual regions.

This Article

  1. Genome Res. 14: 313-318

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