Flux Coupling Analysis of Genome-Scale Metabolic Network Reconstructions

Table 1.

Reaction Coupling Statistics for the H. pylori, E. coli, and S. cerevisiae Metabolic Networks



H. pylori

E. coli

S. cerevisiae
Biomass reaction
No biomass reaction
Biomass reaction
No biomass reaction
Biomass reaction
No biomass reaction

Complex media
Glucose minimal
Complex media
Glucose minimal
Complex media
Glucose minimal
Complex media
Glucose minimal
Complex media
Glucose minimal
Complex media
Glucose minimal
19 (2) 15 (2) 25 (2) 23 (2) 45 (2) 33 (2) 48 (2) 37 (2) 51 (2) 45 (2) 51 (2) 46 (2)
8 (3) 7 (3) 10 (3) 9 (3) 9 (3) 6 (3) 9 (3) 9 (3) 13 (3) 11 (3) 14 (3) 14 (3)
2 (4) 1 (5) 3 (4) 2 (4) 4 (4) 1 (4) 4 (4) 3 (4) 6 (4) 5 (4) 7 (4) 5 (4)
1 (6) 1 (7) 1 (5) 2 (5) 3 (5) 1 (5) 5 (5) 5 (5) 2 (5) 3 (5) 2 (5) 3 (5)
2 (7) 1 (10) 2 (6) 3 (6) 2 (6) 3 (7) 2 (6) 2 (6) 2 (6) 2 (6) 2 (6) 2 (6)
1 (10) 1 (174) 3 (7) 2 (7) 1 (7) 1 (10) 2 (7) 2 (7) 1 (7) 1 (7) 1 (7) 1 (7)
1 (148) 1 (8) 1 (8) 1 (8) 1 (112) 1 (8) 1 (8) 2 (8) 2 (8) 2 (8) 2 (8)
1 (9) 1 (9) 2 (9) 3 (9) 3 (9) 1 (9) 1 (9) 1 (9) 1 (9)
4 (10) 4 (10) 1 (66) 1 (10) 1 (10) 1 (12) 1 (12) 1 (12) 1 (12)
1 (13) 1 (13) 1 (17) 1 (17) 1 (30) 1 (34) 1 (17) 1 (17)
1 (20) 1 (20)
Total reactions in subsets: 248 247 220 213 259 236 252 226 261 248 255 242
Total subsets:
34
26
52
49
68
46
76
64
80
72
82
76
  • The first number in each entry denotes the number of coupled sets; the number in parentheses is the size of the coupled set. For example, “19(2)” signifies that there are 19 coupled sets composed of two reactions.

This Article

  1. Genome Res. 14: 301-312

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