Comparison of the FCF-identified coupled reaction sets for H. pylori with the enzyme subsets identified by Schilling et al. (2002). The latter approach subdivides the network into six smaller subnetworks based on functional classification, and finds subsets for each one of them. The FCF procedure considers the network in its entirety. The reaction names in each row correspond to different coupled reaction sets. Underlined reactions highlight coupling relationships identified only using the FCF method, and the two arrows indicate the coupling of enzyme subsets across functional classifications. Reaction abbreviations can be found in the supplemental material of Schilling et al. (2002).
