Flux Coupling Analysis of Genome-Scale Metabolic Network Reconstructions

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Figure 1
Figure 1

Two reaction fluxes are (1) directionally coupled if the activity of one flux implies the activity of the other without the converse necessarily holding true, (2) partially coupled if the activity of one flux implies the activity of the other and vice versa, or (3) fully coupled if activity of one flux fixes the activity of the other. Reactions in enzyme subsets as defined by Pfeiffer et al. (1999) are exclusively fully coupled. Various types of coupling are related to the flux ratio limits Rmin and Rmax as shown.

This Article

  1. Published in Advance January 12, 2004, doi: 10.1101/gr.1926504 Genome Res. 14: 301-312

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