A Comprehensive Analysis of Allelic Methylation Status of CpG Islands on Human Chromosome 21q

Table 2.

Methylation Status and Characteristics of the 149 CGIs Analyzed


Complete methylation

31

   Promoter or 5′-UTR 5
   CDS or 3′-UTR 14
   Tandem repeat sequence 18
   Both tandem repeat sequence and Promoter or 5′-UTR 1
   Both tandem repeat sequence and CDS or 3′-UTR 5
Null methylation 103
   Promoter or 5′-UTR 78
   CDS or 3′-UTR 2
   Tandem repeat sequence 4
   Both tandem repeat sequence and CDS or 3′-UTR 0
Composite methylation 7
   Promoter or 5′-UTR 2
   CDS or 3′-UTR 2
   Tandem repeat sequence 2
   Both tandem repeat sequence and CDS or 3′-UTR 1
Incomplete methylation 8
   Promoter or 5′-UTR 8
   CDS or 3′-UTR 0
   Tandem repeat sequence 0
   Both tandem repeat sequence and CDS or 3′-UTR


  • Each gene-associated CGI was classified by its location in the gene, namely, promoter, 5′-untranslated region (UTR), coding sequence (CDS), and 3′-UTR. The presence of tandem repeat sequence examined by self-Herr plot is also indicated.

This Article

  1. Genome Res. 14: 247-266

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