
Representative RNA expression patterns of identified midline genes. (A) transducer of erbB-2 1 (Tob1). (B) septin6. (C) adenylate kinase 3 α like 1 (AK3). (D) CD151/tetraspanin (CD151). (E) septin7. (F) annexin II. (G) Homolog of the medaka hatching enzyme ehe 13. (H) annexin IV. (I) prolyl-4- hydroxylase. (J-N) connective tissue growth factor (ctgf). (A-G,I,J) Eight-somite-stage embryos; (H,L,N) 16-18-somite-stage embryos. Orientation of embryos is anterior up, dorsal view(A-G,I,J). Scale bar: 50 μm (A-G,J,L); 25 μm (H,K,M,N). (ad) Adaxial cells; (f) floor plate; (h) hatching gland; (hy) hypochord; (n) notochord; (pr) pronephros; (s) somites.











