TF-DNA binding PPVs (probability–proportionality values) as an indicator TF–DNA binding (refer to equation 3)
|
Sites |
CE training |
CE test |
CB muscle |
|---|---|---|---|
| motif 1 | 5094.98 | 111.67 | 22.27 |
| motif 2 | 24.89 | 12.26 | 6.72 |
| motif 3 | 9.49 | 5.95 | 34.79 |
| ces-2 | 0.58 | 0.75 | 0.48 |
| skn-1 | 0.52 | 0.96 | 1.18 |
| gata
|
0.50
|
0.71
|
1.27
|
-
Motifs 1 through 3 are putative C. elegans muscle regulatory elements. Motifs ces-2, skn-1, and gata are C. elegans regulatory motifs unrelated to muscle expression and used as controls. Different gene-sets tested are given. CE training, C. elegans muscle training set (refer to Table 1); CE test, C. elegans muscle test set; CB Muscle, putative orthologs in C. briggsae of known C. elegans muscle genes (Table 1). The mean of the ratios of binding probabilities are given for the test or training gene set versus 500 random sets. Values greater than 5 are in bold.
