Total number of synonymous substitutions per codon in full-length extracellular domains and the most divergent and least divergent ectodomains from various human, coelacanth and zebrafish protocadherin paralog subgroups
|
Subgroup |
dSECa |
dSEC/branchb |
dShighc |
dSlowd |
Ratio (dShigh/dSlow) |
|---|---|---|---|---|---|
| hα1–α13 | 4.68 | 0.20 | 22.29 | 1.56 | 14.29 |
| hβ2–β15 | 4.64 | 0.17 | 9.41 | 1.27 | 7.40 |
| hγA1–γA12 | 5.43 | 0.26 | 9.55 | 2.53 | 3.78 |
| mα1–α12 | 5.40 | 0.26 | 23.90 | 1.34 | 17.77 |
| mβ2–β22 | 8.02 | 0.21 | 13.63 | 5.77 | 2.36 |
| mγA1–γA12 | 7.23 | 0.34 | 12.70 | 4.42 | 2.87 |
| Dr1γ4–1γ18 | 5.44 | 0.20 | 14.32 | 0.15 | 94.62 |
| Dr1γ19–1γ27 | 5.24 | 0.35 | 20.37 | 0.53 | 38.42 |
| Dr2α8–2α25 | 9.37 | 0.28 | 33.46 | 0 | INF |
| Dr2γ15–2γ31 | 6.02 | 0.19 | 53.32 | 0 | INF |
| Lmα3-α10 | 3.64 | 0.28 | 4.89 | 2.80 | 1.75 |
| Lmγ1-γ19
|
7.76
|
0.22
|
10.04
|
6.33
|
1.59
|
-
↵a Total synonymous substitutions per codon (dS) calculated for the alignment of full-length extracellular domain sequences for each paralog subgroup
-
↵b The average number of substitutions per codon for each branch in the gene tree of each subgroup
-
↵c Total synonymous substitutions per codon calculated for the alignment of the most divergent ectodomain in each subgroup
-
↵d Total synonymous substitutions per codon calculated for the alignment of the least divergent ectodomain in each subgroup
