Extensive and breed-specific linkage disequilibrium in Canis familiaris

Table 3.

Haplotypes inferred at each region and the fraction of chromosomes carrying each haplotype




Frequency
Region
Haplotype
AK
BM
GR
LB
PK
1 GGTICAC 0.09 0.78 0.33 0.20
AGTICAC 0.83 0.10 0.25 0.08
GGCDTTT 0.12 0.10 0.58
GCTICAC 0.38 0.18 0.03 0.20
GCCDTTT 0.41
2 GCTCTTC 0.08 0.30 0.53 0.60
GGTCTTT 0.12 0.60 0.23 0.10
ACATCCT 0.78
ATATCCT 0.68 0.15
ACTCTTC 0.03 0.10 0.08 0.05
3 CATITC 0.65 0.28 0.73 0.50 0.80
GGCDGT 0.24 0.73 0.28 0.28 0.20
4 CCTTATC 0.47 0.38 0.20 0.13 0.55
CCCGTCT 0.09 0.15 0.05 0.38 0.30
AACGTCT 0.13 0.65 0.40
CCCGACT 0.26 0.15
AATTATC 0.35
5 CADCAATAG 0.09 0.45 0.15 0.28 0.60
CAITATCCA 0.35 0.05 0.40 0.25
GGITATCCA 0.03 0.43 0.23 0.30
GGITCTCCA 0.38 0.30
CAITCTCCA 0.09 0.03 0.23 0.03 0.10
6 TCGIGCTT 0.55 0.55
CTADATTT 0.33 0.40 0.28
CCGIGCTT 0.62
CTADATCC 0.12 0.10 0.30
CTAIGCTT 0.06 0.05 0.30
CTAIGCTC 0.30 0.08
TCGDATCC 0.05 0.28
CCGIGCCC 0.18 0.10
7 GCAAGATTA 0.50 0.35 0.15
GCGGGGCCG 0.56 0.25
AGAGCACTA 0.33 0.23
GCAGGGCCG 0.06 0.10 0.28
AGAGCACCG 0.03 0.35
GCGGGACTA 0.28
AGGGCACCG 0.10 0.03 0.10 0.03
8 GIGA 0.59 0.40 0.75 0.70
GDAG 0.32 0.65 0.13 0.08
AIGA 0.20 0.08 0.23
AIGG 0.33
9 CCAATGG 0.53 0.33 0.30 0.28 0.55
TATGCTC 0.20 0.45 0.43 0.33
TCTGCGC 0.18 0.10 0.05 0.05
TATGCGC 0.23 0.10
CCTGCGC 0.23 0.03 0.05
CATGCGC 0.18 0.05 0.08
10 ADTT 0.32 0.18 0.18 0.28 0.88
ADTG 0.18 0.38 0.38 0.30
GIAT 0.06 0.28 0.25 0.20 0.05

GDAT
0.12
0.13
0.15
0.20
0.08
  • Haplotypes that are observed on <5% of all chromosomes are not shown. Alleles for insertion/deletion polymorphisms are: (I) inserted; (D) deleted sequence. Note that the second marker in region 2 is a triallelic SNP. Haplotypes were inferred for these 10 regions since they contain at least four SNPs of ≥0.2 MAF in all breeds, and the SNPs span a distance of at least 9 kb. (AK) Akita; (BM) Bernese Mountain Dog; (GR) Golden Retriever; (LB) Labrador Retriever; (PK) Pekingese.

This Article

  1. Genome Res. 14: 2388-2396

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