A→I editing at different RNA base pairings
|
Match/mismatch |
Subset of Alu |
Total (bp) |
Edits |
Edited % |
|---|---|---|---|---|
| A:U matches | All Alus | 5839 | 465 | 8 |
| Alus with single inverted copy | 581 | 44 | 8 | |
| A:G mismatches | All Alus | 217 | 13 | 6 |
| Alus with single inverted copy | 23 | 0 | 0 | |
| A:C mismatches | All Alus | 1166 | 249 | 21 |
| Alus with single inverted copy | 113 | 24 | 21 | |
| A:A mismatches | All Alus | 264 | 11 | 4 |
| Alus with single inverted copy | 24 | 1 | 4 | |
| Total matches | All Alus | 25,363 | 465 | 1.8 |
| Alus with single inverted copy | 2400 | 44 | 1.8 | |
| Total mismatches | All Alus | 8368 | 273 | 3.3 |
|
|
Alus with single inverted copy
|
769
|
25
|
3.1
|
-
Each edited Alu has been BLAST-aligned to the nearest inverted Alu copy in the same transcript to form a hypothetical double-stranded RNA molecule. The numbers of adenines that are matched (A:U) and mismatched (A:A, A:C, A:G) and the numbers of each class of match/mismatch that are edited have been calculated. The calculations have been performed for all edited Alus and separately for the subset of these that have only a single inverted copy in the same intron. The results were from 159 alignments and 738 edits (all Alus) and 14 alignments and 69 edits (Alus with a single inverted copy in the same intron).
