Figure 5.
Effect of sequence composition on the likelihood of RNA editing. A multiple alignment of all edited Alu sequences was prepared using CLUSTALW. At each position in the alignment, the proportion of edited adenosines was calculated from the number of sequenced edited adenosines and the total number of sequenced adenosines. The sequence composition at each position was calculated from all Alus. For each position in the alignment, the proportion of edited adenosines is compared to the proportion of A, C, G, or T at that position (A-D, respectively).
