Array-based determination of tissue-specific gene expression
|
Gene RefSeq or UniGene ID |
HUGO Gene Symbol |
Gene Name |
T/B Cell Ratio by arraya |
B or T-specific by literatureb |
Refc |
|---|---|---|---|---|---|
| NM_010545 | Ii | Ia-associated invariant chain | 0.003 | B | 1 |
| NM_152839 | Igj | immunoglobulin joining chain | 0.004 | B | 1 |
| NM_008339 | Cd79b | CD79B antigen | 0.006 | B | 1 |
| Mm.780 | Igl-V1 | immunoglobulin λ chain, variable 1 | 0.007 | B | 1 |
| NM_010381 | H2-Ea | histocompatibility 2, class II antigen E α | 0.008 | B | 1 |
| NM_008860 | Prkcz | protein kinase C, ζ | 0.010 | — | |
| NM_010379 | H2-Ab1 | histocompatibility 2, class II antigen A, β 1 | 0.010 | B | 1 |
| NM_008528 | Blnk | B-cell linker | 0.010 | B | 1 |
| NM_025282 | Mef2c | myocyte enhancer factor 2C | 0.011 | B | 2 |
| NM_010389 | H2-Ob | histocompatibility 2, O region β locus | 0.011 | B | 1 |
| NM_009844 | Cd19 | CD19 antigen | 0.011 | B | 1 |
| NM_007643 | Cd36 | CD36 antigen | 0.015 | — | |
| NM_010387 | H2-DMb1 | histocompatibility 2, class II, locus Mb1 | 0.024 | B | 1 |
| NM_010388 | H2-DMb2 | histocompatibility 2, class II, locus Mb2 | 0.037 | B | 1 |
| NM_007549 | Blk | B lymphoid kinase | 0.038 | B | 1 |
| NM_029494 | Rsb30 | RAB30, member RAS oncogene family | 0.041 | — | |
| NM_009845 | Cd22 | CD22 antigen | 0.051 | B | 1 |
| NM_011611 | Tnfrsf5 | tumor necrosis factor receptor superfamily, member 5 | 0.062 | B | 1 |
| NM_010747 | Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.065 | B | 3 |
| NM_007575 | C2ta | class II transactivator | 0.088 | B | 1 |
| NM_008533 | Ly78 | lymphocyte antigen 78 | 0.088 | B | 1 |
| NM_009744 | Bcl6 | B-cell leukemia/lymphoma 6 | 0.106 | — | |
| NM_007758 | Cr2 | complement receptor 2 | 0.107 | B | 4 |
| XM_354702 | none | similar to immunoglobulin ϵ | 0.110 | B | 1 |
| NM_021893 | Pdcd1lg1 | programmed cell death 1 ligand 1 | 0.126 | — | |
| NM_010557 | Il4ra | interleukin 4 receptor, α | 0.142 | — | |
| NM_007778 | Csf1 | colony stimulating factor 1 (macrophage) | 0.226 | — | |
| NM_009852 | Cd6 | CD6 antigen | 4.70 | — | |
| NM_013653 | Ccl5 | chemokine (C-C motif) ligand 5 | 7.72 | T | 5 |
| XM_284241 | Tnfrsf7 | tumor necrosis factor receptor superfamily, member 7 | 10.35 | T | 1 |
| NM_008453 | Klf3 | Kruppel-like factor 3 (basic) | 10.70 | — | |
| NM_009400 | Tnfrsf18 | tumor necrosis factor receptor superfamily, member 18 | 14.82 | T | 6 |
| NM_009192 | Sla | src-like adaptor | 16.72 | — | |
| NM_008353 | Il12rb1 | interleukin 12 receptor, β 1 | 20.91 | T | 1 |
| NM_019436 | Sit | SHP2 interacting transmembrane adaptor | 26.66 | T | 1 |
| NM_008859 | Prkcq | protein kinase C, θ | 27.05 | T | 7 |
| NM_010742 | Ly6d | lymphocyte antigen 6 complex, locus D | 31.17 | — | |
| Mm.123831 | Tcrb-V8.2 | T-cell receptor β, variable 8.2 | 35.75 | T | 1 |
| NM_008091 | Gata3 | GATA binding protein 3 | 40.45 | T | 1 |
| NM_010693 | Lck | lymphocyte protein tyrosine kinase | 40.51 | T | 1 |
| NM_010278 | Gfi1 | growth factor independent 1 | 42.67 | T | 8 |
| NM_011487 | Stat4 | signal transducer and activator of transcription 4 | 49.24 | T | 1 |
| NM_011701 | Vim | Vimentin | 52.19 | — | |
| NM_009122 | Satb1 | special AT-rich sequence binding protein 1 | 56.90 | T | 9 |
| NM_009850 | Cd3g | CD3 antigen, γ polypeptide | 59.09 | T | 1 |
| NM_009344 | Phlda1 | pleckstrin homology-like domain, family A, member 1 | 63.57 | T | 10 |
| NM_007642 | Cd28 | CD28 antigen | 67.64 | T | 1 |
| NM_011346 | Sell | selectin, lymphocyte | 72.79 | — | |
| NM_007648 | Cd3e | CD3 antigen, ϵ polypeptide | 93.03 | T | 1 |
| NM_008979 | Ptpn8 | protein tyrosine phosphatase, non-receptor type 8 | 113.63 | — | |
| NM_009345 | Dntt | deoxynucleotidyltransferase, terminal | 118.86 | — | |
| NM_010583 | Itk | IL2-inducible T-cell kinase | 120.75 | T | 11 |
| NM_011609 | Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 132.72 | — | |
| Mm.123831 | Tcrb-V13 | T-cell receptor β, variable | 167.67 | T | 1 |
| NM_010689 | Lat | linker for activation of T cells | 168.24 | T | 12 |
| NM_009382 | Thy1 | thymus cell antigen 1, θ | 171.82 | T | 1 |
| NM_009829 | Ccnd2 | cyclin D2 | 242.81 | — | |
| Mm.210785 | T cell receptor γ chain | 424.47 | T | 1 | |
| NM_013487
|
Cd3d
|
CD3 antigen, δ polypeptide
|
1532.15
|
T
|
1
|
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↵a T/B Ratio is the array hybridization signal measured in the 100% R1.1 sample divided by that of the 100% A20 sample. Each measurement is the mean of four separate arrays
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↵b According to literature. Blanks indicate that we could not find literature-based evidence for T- or B-cell-specific expression. For 14 of the 17 genes for which there was no literature support for the expression pattern, the same samples have been examined by a reverse transcription-based RNA quantitation assay (Fan et al. 2004); in all cases examined, the results from this orthogonal assay agreed with the results determined in this array experiment (J. Yeakley, J.-B. Fan, and E. Chudin, unpubl.)
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↵c References: Abbas et al. (2003); Hermanson et al. (1988); Yamanashi et al. (1991); Fingeroth (1990); Schall et al. (1988); Nocentini et al. (1997); Isakov and Altman (2002); Scheijen et al. (1997); Dickinson et al. (1992); Park et al. (1996); Siliciano et al. (1992); Zhang et al. (1998)
