The human L1 promoter: Variable transcription initiation sites and a major impact of upstream flanking sequence on promoter activity

Table 1.

L1 elements used in this study


Name

Accession no.

Length 5′-flanking sequence

Nucleotide difference to L1.3 5′-UTR

Retroposition activity (%)
L1.3 N.A. 0 N.A. N.A.
L1A AL137191 295 5 0
L1C AC002980 387 2 132 (h)
L1D AC004200 290 4 80 (h)
L1E AC004704 245 18 0.1 (w)
L1F AC005885 282 4 2.3 (w)
L1G AC005908 57 8 0.1 (w)
L1H AC006027 107 10 3 (w)
L1I AC026113 472 16 0
L1J AC013759 38 12 0
L1K AL021069 403 11 0.3 (w)
L1L AL022399 420 9 0
L1M
AL031586
74
12
0.1 (w)
  • The first column incidates the L1 element designations used in this study. The second column gives the GenBank accession numbers harboring the respective L1 elements. The length of cellular sequence flanking for a given L1 element in the upstream direction is given, as well as the nucleotide difference of each 5′-UTR sequence compared with the 5′-UTR sequence in L1.3. Retrotransposition activities (high and weak) of L1 elements, compared with the activity of L1.3, are given according to Brouha et al. (2003).

This Article

  1. Genome Res. 14: 2253-2260

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