Laurence Lavie; Esther Maldener; Brook Brouha; Eckart U. Meese; Jens Mayer

The human L1 promoter: Variable transcription initiation sites and a major impact of upstream flanking sequence on promoter activity

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.

No influence of 10-bp and 5-bp sequence alterations immediately upstream of the L1.3 5′-UTR on the promoter activity. For instance, flC10-L1.3 is an L1.3 derivative for which the first 10 bp immediately upstream of the 5′-UTR were replaced by the corresponding sequence region in L1C. (G)5 indicates that the first 5 bp immediately upstream of the L1.3 5′-UTR have been altered to G nucleotides.