Laurence Lavie; Esther Maldener; Brook Brouha; Eckart U. Meese; Jens Mayer

The human L1 promoter: Variable transcription initiation sites and a major impact of upstream flanking sequence on promoter activity

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Figure 3.

Results of χ² tests for statistical significance of higher G nucleotide frequencies immediately upstream of (A) the human L1 element start. (B) A significant higher number of G nucleotides in position nucleotide -1 is shown for HERV-W pseudogenes. (C) Human Alu elements do not display such an increase. Thresholds of significance are indicated by horizontal lines.