Analysis of Small Human Proteins Reveals the Translation of Upstream Open Reading Frames of mRNAs

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Figure 1
Figure 1

Identification of a novel short coding sequence by mass spectrometry. (A) MS/MS spectrum corresponding to the peptide QPQPAQNVLAAPR at m/z 695.38 derived from the NM_015532 ORF. The corresponding amino acid differences based on a series of as many as 10 continuous y ions are represented. An asterisk (*) indicates an ion that has lost ammonia from its side chain. (B) Amino acid sequence of the NM_015532 upstream short ORF. The identified peptides are surrounded by rectangles.

This Article

  1. Genome Res. 14: 2048-2052

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