An ORFeome-based Analysis of Human Transcription Factor Genes and the Construction of a Microarray to Interrogate Their Expression

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 1
Figure 1

Creation of the seed set. Known TF genes were gathered from three databases: TRANSFAC, InterPro, and FlyBase. Each gene was manually confirmed to be described as a TF in the literature or annotated as a TF in LocusLink. After removing redundancies and adding some known TFs that were not present in our source databases, our seed set of human TFs contained 1468 members.

This Article

  1. Genome Res. 14: 2041-2047

Preprint Server