Analysis of Human mRNAs With the Reference Genome Sequence Reveals Potential Errors, Polymorphisms, and RNA Editing

Table 5.

Unsupported Mismatches


Genome base

mRNA base

All support

No Genome support
A G 1424 (14.7%) 186 (23.3%)
G A 1675 (17.3%) 90 (11.3%)
C T 1179 (12.2%) 74 (9.3%)
T
C
1358 (14.1%)
168 (21.1%)
  • This table shows that most common mismatched bases between the mRNA and genome sequences in which one is supported by at least three human transcripts, the other by none. The third column reports results from all 9660 instances, and the fourth column shows results from the 796 of these with only support for the mRNA sequence and none for the genome sequence.

This Article

  1. Genome Res. 14: 2034-2040

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