From ORFeomes to Protein Interaction Maps in Viruses

Table 1.

ORFeome and Interaction Studies of Viral Proteomes


Virus

ORFs

Interactions

Interactions/ORF

Reference
Hepatitis C virus (HCV) ∼10a 5 0.50 Flajolet et al. (2000)
Vaccinia virus 266 37 0.14 McCraith et al. (2000)
T7 bacteriophage 55 25 0.45 Bartel et al. (1996)
Potato virus A (PVA) 10a 12 1.20 Guo et al. (2001)
Pea seed-borne mosaic (PSbMV) 10a 8 0.80 Guo et al. (2001)
Wheat streak mosaic virus (WSMV) 10a 12b 1.20 Choi et al. (2000)
Kaposi-sarcoma-associated virus (KSHV)
88
125
1.42
P. Uetz, Y.A. Dong, C. Zeretzke, M. Roupelieva, D. Rose, C. Atzler, and J. Haas in prep.
  • a Number of mature proteins derived from a single precursor. Among the 10 proteins of PVA, PSbMV, and WSMV there are two small proteins (6K1 and 6K2, 6 kD each) whose interactions were not tested in any of the studies presented here.

  • b Approximate number because interactions of overlapping protein fragments were not always assigned to defined mature proteins.

This Article

  1. Genome Res. 14: 2029-2033

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