Large-Scale Mutagenesis of the Yeast Genome Using a Tn7-Derived Multipurpose Transposon

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Figure 7
Figure 7

Diagrammatic summary of phenotypic screening for cisplatin sensitivity. Fifty-one genes conferring sensitivity to cisplatin upon disruption are indicated in functional groups related to DNA damage/repair, transcription, replication, chromatin structure, and ribosomal function. Ungrouped genes function in processes that were not enriched among this set. Standard gene names have been used when available. YCR007C, YDR149C, YKL005C, and YMR110C are functionally uncharacterized.

This Article

  1. Genome Res. 14: 1975-1986

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