Table 1.
Comparison of Ensembl and Manual Gene Annotations of the Region
|
Match type |
Sensitivitya |
Specificitya |
|---|---|---|
| Gene level | 0.94 | 0.83 |
| Transcript level | 0.75 | 0.72 |
| Annotated exons covered completely: all exons | 0.76 | 0.74 |
| Annotated exons covered completely: coding exons | 0.90 | 0.75 |
| Annotated exons with exact matches at boundaries: all exons | 0.63 | 0.57 |
| Annotated exons with exact matches at boundaries: coding exons
|
0.85
|
0.71
|
-
↵a Calculations of sensitivity and specificity represent the success of Ensembl in predicting genes identified by our manual annotation process. Thus, a specificity of 0.83 indicates that 83% of positives in the Ensembl process are true positives by our criteria.
