Location of region on mouse and human chromosomes and dotplot of the breakpoint region. (A) The location of the contig on mouse chromosome 13 and the equivalent regions on human chromosome 6. The segments of interest (0-9) are indicated. Note that on the human chromosome, the regions are split into two blocks, breaking in segment 5. Positions and relative sizes of regions are only approximate; human and mouse chromosomes are shown to different scales. (B) Del36H segment 5 has homology with human chromosome 6p25 and 6p22 at its edges, as well as 3q24 in the center. Between these stretches of homology are two stretches of sequence, BP-1 and BP-2, that do not have any detectable homology with human sequence.
