Figure 2
Tissue-specific genes evolve faster and are more likely to belong to large gene families. (A) Average Ka/Ks ratios with 95% confidence intervals for human/mouse orthologs with tissue-specific, intermediate, and housekeeping gene expression profiles. Kruskal-Wallis rank test, p < 0.001. (B) Average breadth of expression, measured as the mean percentage of the 16 tissues in which a gene was expressed, for human and mouse orphan genes and genes in families of growing size. (C) Average PEMMAX values for human and mouse orphan genes and genes in families of growing size.
