Human, Mouse, and Rat Genome Large-Scale Rearrangements: Stability Versus Speciation

Table 1.

Human, Mouse, and Rat Synteny





Syntenyb
Species
BACs placed
Genome covered by BACsa
Totalc
Per blockd
Mouse vs. Rat 108,680 2.32 Gb mouse, 2.44 Gb rat, 90% 146 blocks, 2.47 Gb mouse and 2.64 Gb rat. 743 BACs, 16.9 Mb mouse and 18.5 Mb rat.
Human vs. Mouse 29,463 1.65 Gb mouse, 1.83 Gb human, 64% 299 blocks, 2.31 Gb mouse and 2.55 Gb human. 98 BACs, 7.9 Mb mouse and 8.5 Mb human.
Human vs. Rat 26,729 1.62 Gb rat, 1.71 Gb human, 60% 295 blocks, 2.42 Gb rat and 2.48 Gb human. 90 BACs, 8.2 Mb rat and 8.4 Mb human.
Human, mouse and rat
21,363
1.41 Gb mouse, 1.47 Gb rat, 1.56 Gb human, 55%
328 blocks, 2.2 Gb mouse, 2.3 Gb rat and 2.4 Gb human.
64 BACs, 6.8 Mb mouse, 7.2 Mb rat, and 7.3 Mb human.
  • a The total number of bases (in Gb) and the percentage of the genome covered by the BACs for each genome involved.

  • b All clones within a block are in the same order and orientation on each genome involved. Blocks with the same orientation were merged without considering gaps, after discarding blocks with size <100 kb or total clone # below 6 for mouse vs. rat, 3 for human vs. mouse or rat, 2 for the three species.

  • c Total number of syntenic blocks identified, total amount of genome covered by the blocks on each genome.

  • d Average number of BACs per block, average block size on each genome involved.

This Article

  1. Genome Res. 14: 1851-1860

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