Characteristics of the IGnT cluster. (A) Organization of the human, mouse, and rat IGnT clusters. Variable and constant exons are indicated. (B) Distribution of CpG islands in the genomic sequences of the human, mouse, and rat IGnT clusters. Shown are ratios of observed to expected CpG dinucleotide frequency of an 800-bp sliding window for the genomic sequences of the IGnT cluster in the three species. (C) A conserved motif and its relative position (negative numbers flanking the motif) to the translation start codon in the human, mouse, and rat IGnT clusters. The probability of finding the motif within 500 nt upstream of the translation start codon is shown within parentheses at the right. (D) Phylogenetic tree of the human, mouse, and rat IGnT variable protein sequences. (E) Percentage identities of a pairwise comparison between two human, mouse, or rat IGnT variable protein sequences.
