Figure 4
Bidirectional promoters function as inseparable units. Normalized luciferase activity is plotted next to each construct, with arrows indicating the direction of transcription. (A) Loss of upstream promoter sequence leads to loss of transcriptional activity, indicating that there are shared elements necessary for full promoter activity in each direction. (B) A similar series of deletion constructs illustrates that a shared 30-bp fragment is able to confer full activity in both directions.
