
Bidirectional gene pairs show correlated expression patterns in microarray experiments. (A) The frequency distribution of Pearson correlation coefficients of 500,000 random gene pairs averaged over 18 published microarray data sets. (B) The frequency distribution of correlation coefficients of nonbidirectional nearest neighbor gene pairs averaged across the 18 microarray experiments. (C) The frequency distribution of correlation coefficients of bidirectional gene pairs averaged across the 18 microarray experiments.











