Elevated Rates of Protein Secretion, Evolution, and Disease Among Tissue-Specific Genes

Table 3.

Kolmogorov-Smirnov Test Probability Results for Significant Differences Between Pairs of Distributions of Tissue-Specific Genes KA/KS Values




Ad

Am

DO

DR

Fb

Fl

HU

He

H3

Ki

Li

Lu

Ov

Pa

Pg

Pl

Pr

Sg

Sc

Sp

TH

Te

Th

Ty

Tr

Ut

Wb

MP

Median Ka/Ks
Fb + + + + + + + + + + + + + + + + + + + + + + + + + 8.25 0.040
Am + + + + + + + + + + + + + + + + + + + + + + + + 7.80 0.041
Ut + + + + + + + + + + + + + 1.95 0.061
H3 + + + + + + + + + + + + 1.90 0.063
Sc + + + + + + + + + + 1.05 0.069
He + + + + + + + + + + + 0.95 0.070
Sg + + + + + + + + 0.65 0.071
Ov + + + + + + + + + + 0.80 0.071
Pl + + + + + + + + 0.90 0.075
Pr + + + + + + + + + 0.80 0.075
Ty + + + + 0.40 0.076
Pa + + + + + + + + 0.70 0.077
DO + + + + + + + + + 0.80 0.078
TH + + + + + + + + 1.00 0.083
Pg + + + + + 0.45 0.083
HU + + + + + + 1.15 0.085
DR + + + + 0.45 0.085
Sp + + + + + + + 0.95 0.087
Ag + + + + + 0.90 0.091
Tr + + + + + + + + + 1.50 0.100
Wb + + + + + + + + + 1.75 0.101
Lu + + + + + + + + + + + 1.70 0.101
Ki + + + + + + + + + + + + + 2.00 0.102
Te + + + + + + + + + + + + + + + 2.05 0.103
Li + + + + + + + + + + + + + + + + + + + 4.00 0.114
Fl + + + + + + + + + + + + + + + + + + + 4.35 0.126
Th

+
+

+

+
+
+



+
+
+
+
+
+
+

+




+

2.25
0.127
  • Tissue rows are sorted according to median KA/KS values. High or low significance (p-value threshold of 0.01) is denoted by + or — signs, respectively. Abbreviations: MP, median probability results for a certain tissue against all other tissues; probability values were used by calculating the negative logarithm of the probability. Ad, Adrenal gland; Am, Amygdala; DO, DOHH2; DR, DRG; Fb, fetal brain; Fl, fetal liver; HU, HUVEC; He, heart; H3, Hep3B; Ki, kidney; Li, liver; Lu, lung; Ov, ovary; Pa, pancreas; Pg, pituitary gland; Pl, placenta; Pr, prostate; Sc, spinal cord; Sg, salivary gland; Sp, spleen; TH, THY; Te, testis; Th, thymus; Ty, thyroid; Tr, trachea; Ut, uterus, Wb, whole blood.

This Article

  1. Genome Res. 14: 54-61

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