A Whole-Genome Mouse BAC Microarray With 1-Mb Resolution for Analysis of DNA Copy Number Changes by Array Comparative Genomic Hybridization

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Figure 5
Figure 5

Array CGH analysis of in vitro transformed RMT18 MEFs derived from a female embryo. (A) CGH profiles of all autosomes and the X-chromosome, showing copy number gains for chromosomes 6, 10, and 19, and copy number loss for chromosome X. (B) Ploidy analysis of RMT18 cells. Normal mouse ES cells were used as a normal diploid control. DNA index is 1.37. (C-E) Chromosome painting of RMT18 metaphase spreads for chromosome 19, X, and 18, respectively.

This Article

  1. Genome Res. 14: 188-196

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