A Whole-Genome Mouse BAC Microarray With 1-Mb Resolution for Analysis of DNA Copy Number Changes by Array Comparative Genomic Hybridization

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4Figure 4
Figure 4

Array CGH analysis of oncogene amplifications in mouse mammary tumors. (A) Southern analysis of tumor DNA using Kras2, Myc, and Ccnd1 specific probes. Tumors 1, 2, and 3 showed amplification of Kras2, Myc, and Ccnd1, respectively. (B) Whole-genome array CGH profiles (left panels) and CGH profiles of the relevant chromosomes (right panels) from mouse mammary tumors 1, 2, and 3. Plotted are log2-transformed hybridization ratios of tumor DNA vs. control DNA. Vertical red bars on each chromosome indicate the positions of Kras2, Myc, and Ccnd1, respectively.

This Article

  1. Genome Res. 14: 188-196

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research