Example of a group from the EGO subset that is extended by OrthoMCL. Five synaptobrevin genes were clustered together by OrthoMCL (GroupID #379767), including yeast SNC1 and SNC2, fly Syb and n-syb, and worm snb-1. Thick solid arrows represent orthology identified by reciprocal best matches, dotted arrows represent “recent” paralogs, and thin solid arrows represent one-way best matches indicating the direction from query to subject (based on BLASTP comparisons). Only snb-1, n-syb, and Syb (dark gray) were identified by the EGO subset (groups TOG257010, TOG272289, TOG273790), and these genes were only grouped because their gene index sequences (TC72314, TC140251, TC134828) formed `triangles' of reciprocal best matches based on BLASTN comparisons with other species not shown in this analysis.
