Trait relationships in mutant mice with CV pathology and mice treated with anesthesia. Traits not measured in the studies are highlighted in gray. Upward arrows indicate that the mutant (or treated) mice had significantly higher trait values than wild-type (or untreated) mice, and downward arrows indicate that the mutant (or treated) mice had significantly lower trait values than wild-type (or untreated mice). Double-headed (horizontal) arrows indicate an insignificant difference between mutant (or treated) and wild-type (or untreated) mice. The red lines indicate the PSN relationships that do not appear to be present in mutant (or treated) mice. (A) Trait relationships for mice with cardiac-specific overexpression of calsequestrin. Ten–12-wk-old mice were anesthetized with 2.5% Avertin (Schmidt et al. 2000). (B) Trait relationships in transgenic mice with overexpression of protein kinase C β2 isoform in myocardium. Eleven-wk-old mice were anesthetized with 2.5% Avertin (Wakasaki et al. 1999) (C) Trait relationships in transgenic mice with reduced brown fat. Twelve-wk-old mice were anesthetized with ketamine and xylazine (Cittadini et al. 1999). (D) Trait relationships in conscious and anesthetized mice. Twelve-wk-old mice were analyzed without anesthesia or with 2.5% tribromoethanol (Kiatchoosakun et al. 2001).
