Figure 4
VISTA plot of DNA sequence conservation in the mouse and human Gdf6 region. Percent nucleotide identities between mouse and human DNA sequences are plotted as a function of position along the mouse sequence (Mayor et al. 2000). The five regulatory domains defined by BAC ends in Fig. 2 are denoted by colored bars under the plot panels. Peaks of evolutionary conservation overlapping Gdf6 exons are shaded blue. Aligned regions of more than 70% identity over 100 bases are shaded pink. The Uqcrb pseudogene exons are connected with a dotted line to reflect extensive splicing variability and exon skipping in the five known spliced ESTs.
