Figure 5
CNSs may bind a negative regulatory factor(s). Greene and coworkers (1994) positioned nine transposon insertions (colored triangles) within the third intron of the knotted1 Class I homeobox gene in maize. These insertions were found as dominant mutants conferring ectopic gene expression and phenotype. Note how they cluster in a region rich in CNSs. The bottom-most plot is a global alignment of the third intron (Vista; Loots et al. 2002), showing bp identity in a 20-bp sliding window.
