Table 2.

Potential Virulence Determinants Which Are Absent or Highly Divergent in Some of the 10 Y. pseudotuberculosis Strains Tested

		354 (O:1b)	Pa3606 (O:1b)	YPIII pIB1 (O:3)	83 (O:3)	Pa3423 (O:3)	197 (O:5b)	141 (O:7)	wla872 (O:7)	SP93422 (O:15)	SP940616 (O:15)
YPO0599-602	Putative adhesin.	-	-	+	+	-	-	-	-	+	+
YPO0947	Putative virulence determinant	+	0.65	+	+	0.75	0.5	+	+	0.7	+
YPO1002	Enterotoxin-like protein	0.6	0.6	+	+	+	+	0.65	+	0.5	+
YPO1003	Putative exported protein	+	0.7	+	+	+	+	0.6	+	0.6	0.65
YPO1004	Putative autotransporter yapH.	+	-	+	+	+	+	-	-	-	+
YPO1898-1917	Yersiniabactin locus.	-	-	-	-	-	-	-	-	+	-
YPO2044	Putative hemolysin activator protein.	+	0.3	+	+	+	0.3	0.3	0.25	0.3	0.3
YPO2045	Putative hemolysin.	0.4	0.4	+	+	0.5	0.4	0.2	0.2	0.3	0.45
YPO2150	LysR-family transcriptional regulator.	+	+	+	+	+	-	-	+	-	-
YPO2490	Putative hemolysin	+	-	0.5	-	-	0.2	0.3	+	-	-
YPO2886	Putative autotransporter yapA.	+	+	-	-	+	+	+	+	+	+
YPO2887	Putative autotransporter yapB.	+	+	0.55	0.7	0.7	0.5	0.7	+	0.6	0.7
YPO3673	Putative insecticidal toxin TccC.	+	+	0.35	0.35	+	+	+	+	0.7	0.75
YPO3674	Putative insecticidal toxin TccC.	+	+	0.4	0.5	+	+	+	+	+	+
YPO3678	Putative insecticidal toxin TcaC.	0.4	0.3	0.5	0.6	0.5	0.5	0.4	0.3	0.4	0.45
YPO3679	Putative insecticidal toxin TcaB.	0.4	0.35	+	+	0.65	0.55	0.6	0.4	0.35	0.4
YPO3681	Putative insecticidal toxin TcaA.	+	+	+	+	+	+	+	+	+	+
YPO3682	LysR-family transcriptional regulator.	+	0.3	+	+	0.45	0.4	0.5	0.7	0.5	0.7
YPO3720	Putative hemolysin activator protein	+	+	0.4	0.4	+	+	0.7	+	0.7	0.75
YPO3883-3885	Colicin and immunity protein	-	-	+	+	-	-	+	-	-	-

Selected genes that may be involved in virulence or host adaptation. Y. pseudotuberculosis strain names are followed by their serotype in parentheses. The presence of a gene is indicated by a plus sign (+), absence by a minus sign (-), and divergence by the signal to control ratio represented numerically.

Application of DNA Microarrays to Study the Evolutionary Genomics of Yersinia pestis and Yersinia pseudotuberculosis