Table 1.
Nucleotide Substitution Rates in Various Regions and Units of the ALS7 Gene
|
Region/unit |
Average ± SD nucleotide substitutions per bp between unitsa (no. of nucleotides analyzed) |
Strains analyzed |
|---|---|---|
| 5′ nonrepetitive domain | 0.002 ± 0.001 (4 × 1311 = 5244) | SC5314, 1161, RIHO13 (two alleles) |
| 3′ domain, nonrepetitive region upstream of VASES region | 0.007 ± 0.007 (5 × 900 = 4500) | SC5314, 1161, var1.7 RIHO13 (two alleles) |
| 3′ domain, nonrepetitive region downstream of VASES region | 0.003 ± 0.001 (5 × 1389 = 6945) | SC5314, 1161, var1.7, RIHO13 (two alleles) |
| 108 bp tandem repeat (all) | 0.156 ± 0.104 (64 × 108 = 6912) | SC5314, 1161, var1.7, RIHO13 (two alleles) |
| First 108 repeat | 0.004 ± 0.005 (5 × 108 = 540) | SC5314, 1161, var1.7, RIHO13 (two alleles) |
| Last 108 repeat | 0.019 ± 0.024 (5 × 108 = 540) | SC5314, 1161, var1.7, RIHO13 (two alleles) |
| Other 108 repeats | 0.101 ± 0.055 (54 × 108 = 5832) | SC5314, 1161, var1.7, RIHO13 (two alleles) |
| All VA/TSES repeats | 0.034 ± 0.033 (83 × 15 = 1245) | SC5314, 1161, RIHO13 (two alleles), CLB42, CLB44, Au90, FJ9, FJ26, jam2c |
| First pair of VA/TSES unit stretchb | 0.000 ± 0.000 (23 × 30 = 690) | SC5314, 1161, RIHO13 (two alleles), CLB42, CLB44, Au90, FJ9, FJ26, jam2C |
| VASES repeats | 0.000 ± 0.000 (41 × 15 = 615) | SC5314, 1161, RIHO13 (two alleles), CLB42, CLB44, Au90, FJ9, FJ26, jam2c, OD8824, W132 |
| VTSES repeats | 0.000 ± 0.000 (42 × 15 = 630) | SC5314, 1161, RIHO13 (two alleles), CLB42, CLB44, Au90, FJ9, FJ26, jam2c, OD8824, W132 |
| 87 bp repeat (all) | 0.025 ± 0.015 (43 × 87 = 2697) | SC5314, 1161, RIHO13 (two alleles), CLB42, CLB44, Au90, FJ9, FJ26, jam2c, gaymc-c, var1.7 |
| 87 bp repeat (first) | 0.007 ± 0.017 (13 × 87 = 1131) | SC5314, 1161, RIHO13 (two alleles), CLB42, CLB44, Au90, FJ9, FJ26, jam2c, gaymc-c |
| 87 bp repeat (middle) | 0.022 ± 0.014 (16 × 87 = 1392) | SC5314, 1161, RIHO13 (one allele), CLB42, CLB44, Au90, FJ9, FJ26, jam2c, gaymc-c |
| 87 bp repeat (last) | 0.008 ± 0.008 (14 × 87 = 1213) | SC5314, 1161, RIHO13 (two alleles), CLB44, FJ26, jam2c, gaymc-c, var1.7 |
| 138 bp repeat | 0.019 ± 0.013 (28 × 138 = 3864) | SC5314, 1161, RIHO13 (two alleles), CLB42, CLB44, Au90, FJ9, FJ26, jam2c, OD8824, W132 |
| 141 bp repeat (all) | 0.053 ± 0.047 (29 × 141 = 4089) | SC5314, 1161, RIHO13 (two alleles) CLB42, CLB44, Au90, FJ9, FJ26, jam2c, gaymc-c, OD8824, W132 |
| 141 bp repeat (last)
|
0.023 ± 0.045 (12 × 141 = 1692)
|
SC5314, 1161, RIHO13 (two alleles), CLB42, CLB44, Au90, FJ9, FJ26, jam2c, gaymc-c, OD8824, W132
|
