Sixty Alleles of the ALS7 Open Reading Frame in Candida albicans: ALS7 Is a Hypermutable Contingency Locus

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Figure 6
Figure 6

Neighbor-joining trees based on genetic distances (uncorrected p) between sequences of individual 108-bp repeats (A), 15-bp VA/TSES repeats (B), 87-bp repeats (C), 138-bp repeats (D), and 141-bp repeats (E). Repeats are labeled as follows: The first digits indicate the strain (up to four digits; names are abbreviated if necessary), followed by a blank space, followed by the name of the allele (using the same nomenclature as in Fig. 3; in some cases the name is incomplete because only one VASES region was cloned and sequenced, and the allele to which it belonged was not determined), followed by a Cif the strain belongs to the GPG cluster, and an N for noncluster. In all panels except B, the next digits give the position of the repeat in the domain, that is, the first unit of its kind in the domain has the number 1. The last unit of its kind in a domain is labeled with an L as the final letter. In B, the position of VA/TSES repeats is designated by two numbers: The first describes the number of the stretch of VA/TSES units in the region, and the second describes the position of the repeat in the stretch; this is followed by an L if it is the last unit in the stretch (e.g., 2.3L is the third and last unit in the second stretch of VA/TSES repeats in the region).

This Article

  1. Genome Res. 13: 2005-2017

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