Automated Detection of Informative Combined Effects in Genetic Association Studies of Complex Traits

Table 3.

Application of DICE to the Association Between Myocardial Infarction and Nine Polymorphisms of the RAA System, Using a Codominant Coding Scheme




Modela

AICci

Δib

#parc

Δsd
Step 0 y = intercept + country 1561.28 2
Step 1e ACE I/D 1558.93 0.00 3 2.35
AGTR1/T-810A 1559.87 0.94 3 1.41
AGTR1/A+39C 1560.51 1.57 3 0.78
Step 1bis f ACE I/D*AGTR1/A+39C 1553.67 0.00 5 7.61
ACE I/D + AGTR1/T-810A 1556.90 3.23 4 4.38
ACE I/D*AGT/M235T 1556.92 3.24 5 4.37
STOP

Final model: y = country + ACE I/D*AGTR1/A+39C



  • n = 1133. See footnotes of Table 1

This Article

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