Allelic Variation in Gene Expression Is Common in the Human Genome

Table 2.

The Allelic Gene Expression Ratios for Seven Genes in Multiple Tissues Measured by Quantitative PCR


Genes

SNP ID

Liver

Kidney

Heart

Othera

No. of fetuses
ZIM2b rs3143 >8.0 >8.0 >8.0 >8.0 3
SNRPNb rs705 >8.0 >8.0 >8.0 >8.0 3
TAP2b rs17034 3.22 ± 1.57 1.90 ± 0.88 4.67 ± 2.88 2.19 ± 0.89 7
ELAC2b rs2523 2.33 ± 0.87 2.55 ± 0.54 2.92 ± 0.73 2.86 ± 0.52 7
DKFZP727G051b rs1837 2.80 ± 1.05 2.32 ± 0.53 2.16 ± 0.41 2.05 ± 0.43 7
UGDH rs1450 1.53 ± 0.72 1.44 ± 0.29 1.39 ± 0.14 1.49 ± 0.35 3
C11orf23
rs1996
1.52 ± 0.27
1.38 ± 0.39
1.52 ± 0.29
1.22 ± 0.16
2
  • The values are the ratios (allele A/allele B) between the two alleles. The values were inverted if less than one (allele B/allele A, when allele B was preferentially expressed). The mean ± SD is provided for allelic gene expression in the various tissues

  • a Several different fetal tissues were used, including adrenal, limb, and lung

  • b Allelic difference in gene expression is significantly deviated from equal expression (95% confidence interval). The confidence interval was generated from heterozygous DNAs

This Article

  1. Genome Res. 13: 1855-1862

Preprint Server