A Subset of Genes That Displayed Allelic Variation in Expression in HuSNP Experiments
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Kidney |
Liver |
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| Gene |
SNP |
Alleles |
Location |
Mean ± SD |
Min-Max |
No. of fetuses |
Mean ± SD |
Min-max |
No. of fetuses |
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| DCTD | rs978 | A, G | 4q35.1 | 2.25 ± 1.70 | 1.30-5.28 | 5 | 4.27 ± 2.70 | 1.17-6.85 | 5 | ||||
| UGDH | rs1450 | C+, T | 4p15.1 | 5.54 ± 6.36 | 1.04-10.03 | 2 | 1.54 ± 0.27 | 1.35-1.74 | 2 | ||||
| RAI14 | rs1390 | A, G+ | 5p13.3-p13 | 3.38 ± 3.28 | 1.23-1.75 | 3 | 5.64 ± 3.06 | 2.81-8.88 | 3 | ||||
| RASGRF2 | rs1589 | C, T+ | 5q13 | 4.53 ± 4.62 | 1.26-7.80 | 2 | 1.58 | 1.58-1.58 | 1 | ||||
| TAP2 | rs17034 | A, G | 6p21.3 | 3.40 ± 2.97 | 1.40-7.79 | 4 | 1.96 ± 0.61 | 1.53-2.40 | 2 | ||||
| DKFZP727G051 | rs1837 | C, T | 9q33.3 | 2.00 ± 1.46 | 1.17-4.20 | 4 | 1.68 ± 0.66 | 1.13-2.65 | 4 | ||||
| PAPPA | rs1405 | C, T | 9q33.1 | 2.77 ± 2.00 | 1.01-4.93 | 4 | 6.85 | 6.85-6.85 | 1 | ||||
| GRF2 | rs1772 | A, G+ | 9q34.3 | 1.47 | 1.47-1.47 | 1 | 6.08 | 6.08-6.08 | 1 | ||||
| VAV2 | rs16763 | A, C+ | 9q34.1 | 3.14 ± 1.85 | 1.12-4.74 | 3 | 4.18 ± 2.13 | 1.31-6.44 | 4 | ||||
| TRIM22 | rs2179 | C, G | 11p15 | 4.37 ± 4.18 | 1.51-9.18 | 3 | 3.54 ± 2.53 | 1.13-6.29 | 4 | ||||
| DSCAML1 | rs16867 | C, T | 11q23 | 6.06 ± 3.37 | 2.94-9.62 | 3 | 5.45 | 5.45-5.45 | 1 | ||||
| VELI1 | rs1537 | C, G | 12q21 | 1.64 ± 0.14 | 1.54-1.73 | 2 | 5.05 ± 2.87 | 3.01-8.33 | 3 | ||||
| FLJ13639 | rs2735 | C, G+ | 13q14.2 | 3.17 ± 2.03 | 1.74-4.61 | 2 | 4.57 | 4.57-4.57 | 1 | ||||
| HTR2A | rs3125 | C+, G | 13q14-q21 | 1.06 | 1.06-1.06 | 1 | 16.46 | 16.46-16.46 | 1 | ||||
| LOC51131 | rs2980 | A+, G | 13q14.12 | 1.29 | 1.29-1.29 | 1 | 6.96 | 6.96-6.96 | 1 | ||||
| SNRPN | rs705 | C+, T | 15q12 | 5.4 | 5.40-5.40 | 1 | 5.21 | 5.21-5.21 | 1 | ||||
| IPW | rs691 | C, T+ | 15q12 | 6.44 ± 4.24 | 1.88-10.26 | 3 | 3.73 | 3.73-3.73 | 1 | ||||
| LOC145622 | rs17068 | C+, G | 15q11.2 | 2.41 | 2.41-2.41 | 1 | 1.85 | 1.85-1.85 | 1 | ||||
| ELAC2 | rs2523 | C, T+ | 17p11.2 | 4.07 | 4.07-4.07 | 1 | 2.28 | 2.28-2.28 | 1 | ||||
| KRT13 | rs1031 | G, T | 17q21-q23 | 3.92 ± 3.25 | 1.05-7.45 | 3 | 4.00 ± 2.55 | 1.12-5.98 | 3 | ||||
| ZIM2 | rs3143 | A, G+ | 19q13.4 | 4.59 ± 2.34 | 2.93-6.24 | 2 | 5.72 | 5.72-5.72 | 1 | ||||
| ARHGAP8 | rs33329 | A, G | 22q13.31 | 2.40 ± 0.48 | 1.79-2.95 | 4 | 1.95 ± 1.27 | 1.18-3.86 | 4 | ||||
| RANGAP1
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rs1953
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A, G
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22q13
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3.75 ± 3.83
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1.08-9.26
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4
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2.32 ± 1.22
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1.09-3.80
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4
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A complete list of all genes can be found in the Supplemental Table. The values are the ratios (allele A/allele B) between the two alleles. The values were inverted if less than one (allele B/allele A, when allele B was preferentially expressed). The allele A and allele B are the first base and second base, respectively. The bases are the ones defined in WIAF markers. They are complementary to the bases in rs if sequences described in WIAF are in opposite orientation to the sequences described in rs. The preferentially expressed allele is labeled with “+,” which is selected if the allele is preferentially expressed in at least 80% of samples.
