
Leave-one-out cross-validation. Histograms of percentile ranks obtained after removing a gene from a query list of genes, building a cassette around the remaining query genes, and then scoring the held-out gene. Open bars show the histogram obtained from random queries ranging in size from 4 to 50; black bars show the histogram obtained from all the queries used in this study. The inset is an expanded view of the highest-scoring genes.











