Table 2.
Highly Differentially Expressed Genes
|
|
|
|
25-mer arrays |
Long oligo v1 arrays |
Long oligo v2 arrays |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniGene cluster |
Symbol |
Gene description |
M |
Fold
diff.a |
Rankb |
M |
fold
diff.a |
Rankb |
M |
Fold
diff.a |
Rankb |
|||||||||||
| Among 10 most highly differentially expressed in K562 RNA sample on at least one array type | ||||||||||||||||||||||
| Hs. 2841 | NMU | Neuromedin U | 4.10 | 17.2 | <1% | 3.43 | 10.8 | <1% | 3.14 | 8.8 | <1% | |||||||||||
| Hs. 289105 | SSX2 | Synovial sarcoma, X breakpoint 2 | 4.47 | 22.2 | <1% | 2.58 | 6.0 | <1% | 2.91 | 7.5 | <1% | |||||||||||
| Hs. 128231 | GAGEB1 | G antigen, family B, 1 | 2.99 | 7.9 | <1% | 2.99 | 7.9 | <1% | 2.58 | 6.0 | <1% | |||||||||||
| Hs. 169536 | RHAG | Rhesus blood group-assoc glycoprotein | 2.56 | 5.9 | <1% | 2.18 | 4.5 | <1% | 2.32 | 5.0 | <1% | |||||||||||
| Hs. 37860 | KLF1 | Kruppel-like factor 1 (erythroid) | 2.93 | 7.6 | <1% | 2.32 | 5.0 | <1% | 1.72 | 3.3 | <1% | |||||||||||
| Hs. 1861 | MPP1 | Membrane protein, palmitoylated 1, 55 kDa | 2.46 | 5.5 | <1% | 1.87 | 3.7 | <1% | 2.40 | 5.3 | <1% | |||||||||||
| Hs. 99962 | PRG2 | Proteoglycan 2, bone marrow | 2.01 | 4.0 | <1% | 1.99 | 4.0 | <1% | 2.69 | 6.5 | <1% | |||||||||||
| Hs. 77439 | PRKAR2B | cAMP-dependent protein kinase reg 2 beta | 2.44 | 5.4 | <1% | 2.04 | 4.1 | <1% | 2.15 | 4.4 | <1% | |||||||||||
| Hs. 184585 | LMO2 | LIM domain only 2 (rhombotin-like 1) | 2.81 | 7.0 | <1% | 1.59 | 3.0 | <1% | 2.22 | 4.7 | <1% | |||||||||||
| Hs. 188021 | KCNH2 | Potassium voltage-gated channel H2 | 2.05 | 4.2 | <1% | 1.71 | 3.3 | <1% | 2.73 | 6.6 | <1% | |||||||||||
| Hs. 372513 | GYPB | Glycophorin B (includes Ss blood group) | 2.33 | 5.0 | <1% | 1.84 | 3.6 | <1% | 2.32 | 5.0 | <1% | |||||||||||
| Hs. 30743 | PRAME | Preferentially expressed antigen in melanoma | 2.23 | 4.7 | <1% | 2.13 | 4.4 | <1% | 2.10 | 4.3 | <1% | |||||||||||
| Hs. 78601 | UROD | Uroporphyrinogen decarboxylase | 2.21 | 4.6 | <1% | 1.99 | 4.0 | <1% | 2.02 | 4.0 | <1% | |||||||||||
| Hs. 1985 | SPTA1 | Spectrin, alpha, erythrocytic 1 (elliptocytosis 2) | 2.89 | 7.4 | <1% | 1.00 | 2.0 | <2% | 2.17 | 4.5 | <1% | |||||||||||
| Hs. 3132 | STAR | Steroidogenic acute regulatory protein | 2.95 | 7.7 | <1% | 1.47 | 2.8 | <1% | 1.59 | 3.0 | <1% | |||||||||||
| Hs. 158213 | SPAG6 | Sperm associated antigen 6 | 2.93 | 7.6 | <1% | 1.19 | 2.3 | <1% | 1.52 | 2.9 | <1% | |||||||||||
| Hs. 194759 | SSX1 | Synovial sarcoma, X breakpoint 1 | 2.39 | 5.3 | <1% | -0.37 | -1.3 | >2%c | 3.11 | 8.6 | <1% | |||||||||||
| Hs. 765 | GATA1 | GATA binding protein 1 (globin transcript. factor 1) | 2.36 | 5.1 | <1% | 2.43 | 5.4 | <1% | 0.00 | -1.0 | >2%c | |||||||||||
| Hs. 178749 | SSX3 | Synovial sarcoma, X breakpoint 3 | 2.78 | 6.8 | <1% | 1.17 | 2.2 | <1% | 0.04 | 1.0 | >2%d | |||||||||||
| Hs. 176660 | GAGE1 | G antigen 1 | 2.79 | 6.9 | <1% | 1.11 | 2.2 | <1% | 0.03 | 1.0 | >2%d | |||||||||||
| Hs. 170076 | VCY | Variable charge, Y chromosome | 0.06 | 1.0 | >2%c | 0.08 | 1.1 | >2%c | 2.51 | 5.7 | <1% | |||||||||||
| Hs. 176615 | COLEC10 | Collectin subfamily member 10 (C-type lectin) | 0.02 | 1.0 | >2%d | -0.20 | -1.1 | >2%d | 2.50 | 5.7 | <1% | |||||||||||
| Among 10 most highly differentially expressed in pool RNA sample on at least one array type | ||||||||||||||||||||||
| Hs. 287820 | FN1 | Fibronectin 1 | -5.78 | -54.8 | >99% | -5.46 | -44.0 | >99% | -6.44 | -86.6 | >99% | |||||||||||
| Hs. 350470 | TFF1 | Trefoil factor 1 | -5.29 | -39.1 | >99% | -5.54 | -46.5 | >99% | -5.58 | -47.8 | >99% | |||||||||||
| Hs. 93194 | APOA1 | Apolipoprotein A-I | -4.36 | -20.6 | >99% | -4.28 | -19.4 | >99% | -5.74 | -53.3 | >99% | |||||||||||
| Hs. 111779 | SPARC | Secreted protein, acidic, cysteine-rich | -4.22 | -18.6 | >99% | -4.53 | -23.2 | >99% | -5.12 | -34.8 | >99% | |||||||||||
| Hs. 1252 | APOH | Apolipoprotein H (beta-2-glycoprotein I) | -4.69 | -25.9 | >99% | -3.54 | -11.6 | >99% | -5.43 | -43.1 | >99% | |||||||||||
| Hs. 324746 | AHSG | Alpha-2-HS-glycoprotein | -4.77 | -27.2 | >99% | -3.99 | -15.9 | >99% | -4.90 | -29.8 | >99% | |||||||||||
| Hs. 181244 | HLA-A | Major histocompatibility complex, class I, A | -5.40 | -42.1 | >99% | -3.59 | -12.0 | >99% | -4.67 | -25.5 | >99% | |||||||||||
| Hs. 74034 | CAV1 | Caveolin 1 | -5.35 | -40.8 | >99% | -4.01 | -16.1 | >99% | -4.00 | -16.0 | >99% | |||||||||||
| Hs. 137476 | PEG10 | Paternally expressed 10 | -5.50 | -45.3 | >99% | -3.76 | -13.5 | >99% | -4.07 | -16.8 | >99% | |||||||||||
| Hs. 284176 | TF | Transferrin | -4.69 | -25.9 | >99% | -3.38 | -10.4 | >99% | -4.86 | -29.1 | >99% | |||||||||||
| Hs. 289114 | TNC | Tenascin C (hexabrachion) | -4.82 | -28.3 | >99% | -3.05 | -8.3 | >99% | -4.87 | -29.3 | >99% | |||||||||||
| Hs. 95972 | SILV | Silver homolog (mouse) | -3.10 | -8.5 | >99% | -5.14 | -35.4 | >99% | -4.45 | -21.8 | >99% | |||||||||||
| Hs. 119651 | GPC3 | Glypican 3 | -4.87 | -29.3 | >99% | -3.17 | -9.0 | >99% | -3.98 | -15.8 | >99% | |||||||||||
| Hs. 118787 | TGFBI | Transforming growth factor, beta-induced, 68 kDa | -3.94 | -15.4 | >99% | -2.89 | -7.4 | >99% | -4.63 | -24.7 | >99% | |||||||||||
| Hs. 1741 | ITGB7 | Integrin, beta 7 | -2.26 | -4.8 | >98% | -4.04 | -16.5 | >99% | -4.46 | -22.1 | >99% | |||||||||||
| Hs. 75431 | FGG | Fibrinogen, gamma polypeptide | -4.96 | -31.1 | >99% | -2.63 | -6.2 | >99% | -2.05 | -4.1 | >98% | |||||||||||
| Hs. 585 | APOB | Apolipoprotein B | -4.88 | -29.5 | >99% | -4.83 | -28.4 | >99% | 0.57 | 1.5 | <98%c | |||||||||||
| Hs. 621 | LGALS3 | Lectin, galactoside-binding, soluble, 3 (galectin 3) | -4.54 | -23.2 | >99% | -4.32 | -20.0 | >99% | 0.25 | 1.2 | <98%d | |||||||||||
| Hs. 750 | FBN1 | Fibrillin 1 (Marfan syndrome) | -3.52 | -11.5 | >99% | -4.39 | -21.0 | >99% | 0.03 | 1.0 | <98% | |||||||||||
| Hs. 1244 | CD9 | CD9 antigen (p24) | -4.94 | -30.7 | >99% | 0.01 | 1.0 | <98%d | -2.69 | -6.5 | >98% | |||||||||||
| Hs. 41270 | PLOD2 | Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -4.97 | -31.3 | >99% | -0.01 | -1.0 | <98%d | -2.36 | -5.2 | >98% | |||||||||||
|
Hs. 118786
|
MT2A
|
Metallothionein 2A
|
-0.57
|
-1.5
|
<98%c
|
-4.41
|
-21.3
|
>99%
|
-0.71
|
-1.6
|
<98%c
|
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↵a Positive numbers indicate higher expression in K562 RNA, and negative numbers indicate higher expression in pool RNA
-
↵b Rank of M value for this gene on this array type (<1%, top 1%; <2%, between 1 and 2%; >2%, not in top 2%; >99%, bottom 1%; >98%, 98-99%; <98%, not in bottom 2%)
-
↵c Predicted to recognize different splice variant(s) according to Acembly gene predictions, UCSC Genome Browser, http://genome.ucsc.edu
-
↵d Low signal intensity (A below median) for this measurement
