Comparative Complete Genome Sequence Analysis of the Amino Acid Replacements Responsible for the Thermostability of Corynebacterium efficiens

Table 3.

Amino Acid Composition of Protein Coding Regions

	Number			Ratio (%)^a
Amino acid	*C. glutamicum*	*C. efficiens*	*C. glutamicum*	*C. efficiens*	P^b
Ala	107,484	122,084	10.58	10.44
Arg	57,210	79,096	5.63	6.76	^***
Asn	33,710	28,875	3.32	2.47	^***
Asp	59,858	74,866	5.89	6.40	^***
Cys	7643	10,706	0.75	0.92
Gln	34,477	40,943	3.39	3.50
Glu	63,816	70,689	6.28	6.04	^*
Gly	81,344	115,628	8.01	9.88	^***
His	22,050	33,308	2.17	2.85	^***
Ile	57,899	57,934	5.70	4.95	^***
Leu	99,098	115,556	9.76	9.88
Lys	35,527	26,882	3.50	2.30	^***
Met	22,217	22,860	2.19	1.95	^*
Phe	37,182	35,530	3.66	3.04	^***
Pro	48,961	62,331	4.82	5.33	^***
Ser	65,246	61,183	6.42	5.23	^***
Thr	62,400	74,898	6.14	6.40	^*
Trp	15,465	14,339	1.52	1.23	^*
Tyr	22,164	21,488	2.18	1.84	^**
Val	81,846	100,565	8.06	8.60	^***
Total	1,105,597	1,169,761

↵a The ratio is the percentage of the number of a given amino acid to the total number of amino acids
↵b P is the significant difference level by z test
↵* P < 0.05
↵** P < 0.01
↵*** P < 0.001

This Article

Genome Res. 2003. 13: 1572-1579

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