Functional Annotation of RIKEN Mouse cDNA Clones Using GNF Expression Atlas
- Genomics Institute of the Novartis Research Foundation (GNF), San Diego, California 92121, USA
This extract was created in the absence of an abstract.
Annotation of novel cDNAs relies on multiple lines of evidence, including gene structure, predicted ORFs, and predicted protein motifs. Insight into function also relies on expression profiling, through querying EST databases of direct experimentation.
High-throughput gene expression profiling, by use of spotted arrays or oligo chip methods, has become an important tool for investigating transcriptional activity. Among cDNAs predicted to encode related proteins, different expression patterns can suggest functional specialization. Additionally, common expression patterns can serve to group …
