Exon Structure Analysis, Ortholog Identification, and SNP Candidate Screening by Mapping Mouse RIKEN Sequences to Multiple Genome Assemblies
- Genomics Institute of the Novartis Research Foundation (GNF), San Diego, California 92121, USA
This extract was created in the absence of an abstract.
Mapping RIKEN full-length cDNAs (The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team 2002) to the genome assemblies enables a variety of analyses to be performed. First, exon structure can be determined, and coding and noncoding regions can be inferred, due to different average exon length. In some cases, the alternative exon structures may be identified at this stage. Second, chromosome position can be used to identify the correct ortholog in human, for which functional data may be available. Third, intronless genes can be identified …
