Figure 5
Annotation interface for clone B930030L03, a potential target for NMD-mediated instability. The CDS region of this clone was annotated from positions 401 (colored diamond) to 1078 (colored triangle), based on similarity with cytokine inducible SH-2-containing protein 3. The CDS for this clone violates the NMD rule for termination codons; the stop codon position (1078, colored triangle) is located 191 bases upstream from the last splice junction (1269, open diamond); thus, such transcripts in the cell may be targets for degradation by the NMD system.
