Table 1.
Family Classification of GPCRs
|
|
Number of genes |
Number of known genes (against MGI) |
Number of new genes (against MGI)a |
Number of novel GPCRsb |
Number of orphan GPCRs |
|---|---|---|---|---|---|
| Family A (rhodopsin-like) | 165 | 134 | 31 | 8 | 45 |
| Family B (secretin-like) | 24 | 16 | 8 | 13 | |
| Family C (metabotropic glutamate/pheromone) | 11 | 4 | 7 | 4 | 4 |
| Family D (fungal pheromone-STE2/MAM2) | |||||
| Family E (fungal pheromone-STE3/MAP3) | |||||
| Family F (slime mold cAMP receptors) | 1 | 1 | 1 | 1 | |
| Frizzled/smoothened family | 8 | 8 | |||
| Vomeronasal receptor (V1R & V3R) | 1 | 1 | 1 | 1 | |
| Ocular albinism proteins | 1 | 1 | 1 | ||
| Others | 2 | 2 | 2 | ||
|
Total
|
213
|
165
|
48
|
14
|
67
|
