Table 1.
CD Families Identified and Their Description With CD Subclass Assignments
|
CD family |
Description |
CD subclass(es) |
|---|---|---|
| Chromodomain-Helicase-DNA-binding domain (CHD) | ||
| Subfamily 1: CHD-1/2 | General description: 2 CDs near N-terminal and ATP-department helicase region | O and H |
| Subfamily 2: CHD-3/4 | Additional RING and/or PHD DNA-binding domains near N-terminal | P and J |
| Subfamily 3: CHD-5 | Additional SANT and/or BRK domains near C-terminal | Q and I |
| Histone methyltransferase | Contain SET flanked by PreSET and PostSET domains | X |
| HP1 | Containing 2 CDs | S and T |
| Polycomb (Pc) | Homologs of D. melanogaster Polycomb protein | B |
| Msl-3 homolog | Homologs of Msl-3 protein of D. melanogaster | E |
| Histone acetyltransferases | Contain a putative acetyltransferase domain near C-terminal | F |
| Retinoblastoma-binding protein 1 (RBBP1) | Proteins containing TUDOR and BRIGHT domains, binds to Retinoblastoma (Rb) protein | E |
| Enoyl-CoA hydratase | Contain EnoylCo A domain | L |
| SWI3 | SWI/SNF-related protein with SANT DNA-binding domain | G |
| Ankyrin family | A CD near the N-terminus and 3 ankyrin repeats near the C-terminus of protein | L |
| Chromomethyltransferase | DNA methylases containing CD | M |
| Integrases | Plant CD-containing proteins with reverse transcriptase and intergrase domains | W |
|
AAAs
|
ATPases proteins of yeasts
|
A
|
-
Identification of CD families was done previously (K. Tajul-Arifin, R. Teasdale, and J.S. Mattick, in prep.). All except three CD families, chromomethyltransferase, integrases, and AAAs families, are represented in mouse genome
