Table 6.
Comparison of IAP and IAP-Related-Family Proteins of Humans and Mice
|
Protein |
Human |
Mouse |
NCBI |
RIKEN |
|---|---|---|---|---|
| NAIP (BIRC1) | + | + | 6679007 | N/A |
| cIAP1 (BIRC2) | + | + | 6680695 | E130019N06 |
| cIAP2 (BIRC3) | + | + | 6680697 | N/A |
| XIAP (BIRC4) | + | + | 20983625 | N/A |
| Survivin (BIRC5) | + | + | 6753089 | 5830459C16 |
| Apollon (BIRC6) | + | + | 20985107 | B230120J06 |
| ML-IAP (BIRC7) | + | + | Not found | E130019N06 |
| ILP2 (BIRC8) | + | - | Not found | N/A |
| Smac (DIABLO) | + | + | 8953909 | 4933428M04 |
| HtrA2 | + | + | 5739487 | 2610024J09 |
|
XAF
|
+
|
+
|
Not found
|
B530033B21
|
-
The IAPs and IAP-agonists (Smac; HtrA2; XAF) of humans and mice are compared. The murine cDNAs found exclusively in the RIKEN database are indicated. (N/A) Not applicable, indicating the data was already present at NCBI. In mice, approximately six NAIP genes have been identified in a cluster on chromosome 13. At least three of these are transcriptionally active and likely to encode functional proteins (Huang et al. 1999; Endrizzi et al. 2000)
