Figure 2
(A) Identification of 373 LPS-responsive transcripts conserved between the mouse strains, or known to be involved in TLR4-mediated LPS signaling; 347 transcripts were identified as enriched in BMM compared to nonmacrophage tissues in the READ expression database. Thirteen of these genes (4%) were also induced by LPS across the time course in the LPS-responsive mouse strains C3H/ARC and BALB/c.
(B) Annotation of the 373 LPS responsive transcripts. Transcripts were binned into functions based on the Gene Ontology terms ascribed to each clone during the FANTOM2 process.
